Associate Professor

Oksana Shynlova

Urogynaecology - Physiology

PhD

Headshot of Dr. Shynlova
Location
Mount Sinai Hospital
Research Interests
mechanical and endocrine signals, oestrogen therapy, pelvic floor disorders, platlet rich plasma, preterm birth, regulation of parturition, urine-derived pluripotent stem cells
Appointment Status
Primary

Dr. Oksana Shynlova is a basic scientist dedicated to advancing maternal-fetal medicine and mature women's health. Dr. Shynlova obtained her Ph.D. in Biochemistry from the Palladin Institute of Biochemistry at the National Academy of Sciences in Ukraine. She worked as a Junior Scientist at the Institute of Biochemistry, where her research focused on investigating membrane mechanisms regulating uterine contractility. After moving to Canada, Dr. Shynlova joined the laboratory of Dr. Stephen Lye as a Research Scientist in the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital in Toronto. Her research focused on molecular mechanisms of the regulation of myometrial functions during pregnancy and labour, specifically the role of mechanical and endocrine signals. Dr. Shynlova has extensive experience with animal and human studies of Preterm Labour's etiology (PTL). She established multiple animal models of obstetrical/gynecologic events, including artificial menopause, pseudopregnancy, unilateral pregnancy, progesterone-delayed labour, infection-induced and sterile PTL models. Her current interest is in improving the identification of women at high risk for spontaneous PTL and using the animal models of PTL for developing new therapeutic interventions for its prevention. Dr. Shynlova was awarded the CIHR grant: Catalyzing Innovation in Preterm Birth Research: "MRI of Cervical Morphology and Maternal Serum Blood Markers Predict Spontaneous Human Preterm Birth". Dr. Shynlova's work has resulted in 70 peer-reviewed publications, four reviews, and four invited chapters.

In 2012, Dr. Shynlova joined the Department of Obstetrics & Gynecology at the University of Toronto as an Assistant Professor. In collaboration with colleagues from the Division of Urogynecology and Reconstructive Pelvic Surgery at Mount Sinai Hospital, Dr. Shynlova is researching the fundamental molecular mechanisms of pelvic floor disorders (Stress Urinary Incontinence and Pelvic Organ Prolapse) in mature women. She has published ten manuscripts on this topic.

 

Research Synopsis

 

Research by Dr. Shynlova can be found under the citation Oksana Shynlova.